Walden PUBH6170 assignment 2

Biology ofAsthmaandAllergicDisease

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The primary objective of this assignment is to introduce you to the major biological concepts that are associated withasthmaandallergicdisease. This Application focuses on the role of various biological processes involved in the chronic illnesses ofasthmaand allergy. Complete the following steps.

1. Read the article by Dale Umetsu and Rosemarie DeKruyff, “The Regulation of Allergy andAsthma.”
   • Umetsu, D. T., & DeKruyff, R. H. (2006). The regulation of allergy andasthma. Immunological Reviews, 212(1), 238–255. Retrieved from the Walden Library Academic Search Premier database. (AN 21667826)
2. Read Chapter 10, “The Respiratory System: Exchange of Gases” in the course text, Human Biology: Concepts and Current Issues.
   
3. Read a selection of the review articles presented below to gain a better or deeper understanding of the topic and help you choose a focus area. For your Application Assignment you must also find at least three primary research articles in your area of interest. You may use the review articles in your Application paper, but primary research is required for your research section. Using less than three primary research articles will result in a deduction of points.

   In the first application, you were given some focus areas. This time, you will do your own research to choose a biological focus; a specific area that interests you. Examples may include the “hygiene hypothesis,” windows of exposure, nutrition and gastrointestinal flora, helminth infections, Tregs, and NKT cells. Read the appropriate optional articles, and then locate additional review and primary research articles on your area of interest.

   • Devereux, G. (2006). The increase in the prevalence ofasthmaand allergy: Food for thought. Nature Reviews Immunology, 6(11), 869–< /font>874. Retrieved from the Walden Library Academic Search Premier database. (AN 22848496)
     
   • Tantisira, K. G., & Weiss, S. T. (2006). The pharmacogenetics ofasthmatherapy. Current Drug Targets, 7(12), 1697–1708. Retrieved from the Walden Library Academic Search Premier database. (AN 23278588)
     
   • Umetsu, D. T., Meyer, E. H., & DeKruyff, R. H. (2007). Natural killer T cells regulate the development ofasthma. International Reviews of Immunology, 26(1/2), 121–< /font>140. Retrieved from the Walden Library Academic Search Premier database. (AN 24515668)
     
   • Wohlleben, G., & Erb, K. J. (2006). Immune stimulatory strategies for the prevention and treatment ofasthma. Current Pharmaceutical Design, 12(25), 3281–? < /font>3292. Retrieved from the Walden Library Academic Search Premier database. (AN 22139036)
     
   • Yeatts, K., Sly, P., Shore, S., Weiss, S., Martinez, F., & Geller, A. et al. (2006). A brief targeted review of susceptibility factors, environmental exposures,asthmaincidence, and recommendations for futureasthmaincidence research. Environmental Health Perspectives, 114(4), 634–< /font>640. Retrieved from the Walden Library Academic Search Premier database. (AN 20814567)

4. Write a five page (body; double-spaced) review of the topic from a public health biology perspective. In your review, include the following:
   
   
   1. Explain the biological basis ofasthmaandallergicdisease, including an introduction to your chosen focus area;
   2. Discuss some of the recent (within five years) and current research on the biological focus area you chose, including study aim, methods, and results of the studies you discuss;
   3. Explain the value and application of the above research findings to public health, citing the studies as needed, and providing some examples of how this information is or can be used in public health policy, programs, and practice.

   Your paper must provide APA-formatted references for all resources used and adhere to APA style and format. APA style headers will be expected for the three subsections of biological basis, research, and public health application. Use subheaders as needed. A title page and a reference page is required. An abstract is optional. Use your APA manual, or get help from the Writing Center if you need it

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